3. The ILRN gene encodes a protein that acts as an antagonist to interleukin receptors. This gene has three alleles represented as A*1, A*2, and A*3. In a study on the relationship between genotype and chronic pain sensitivity, data was collected on the ILRN genotype of 100 people as follows: 50 A*1/A*1 26 A*1/A*2 A*1/A*3 4 10 0 10 A. Calculate the frequency of each allele. B. Determine how many people there would be of each genotype if the population were in Hardy- Weinberg equilibrium and use the Chi-squared test to evaluate how well these expectation fit the A*2/A*2 A*2/A*3 A*3/A*3

Concepts of Biology
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ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:Samantha Fowler, Rebecca Roush, James Wise
Chapter10: Biotechnology
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Problem 13CTQ: Identify a possible advantage and a possible disadvantage of a genetic test that would identify...
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3. The ILRN gene encodes a protein that acts as an antagonist to interleukin receptors. This gene has
three alleles represented as A*1, A*2, and A*3. In a study on the relationship between genotype and
chronic pain sensitivity, data was collected on the ILRN genotype of 100 people as follows:
50
A*1/A*1
26
A*1/A*2
4
A*1/A*3
10
A*2/A*2
A*2/A*3
A*3/A*3
0
10
A. Calculate the frequency of each allele.
B. Determine how many people there would be of each genotype if the population were in Hardy-
Weinberg equilibrium and use the Chi-squared test to evaluate how well these expectation fit the
observed data
Transcribed Image Text:3. The ILRN gene encodes a protein that acts as an antagonist to interleukin receptors. This gene has three alleles represented as A*1, A*2, and A*3. In a study on the relationship between genotype and chronic pain sensitivity, data was collected on the ILRN genotype of 100 people as follows: 50 A*1/A*1 26 A*1/A*2 4 A*1/A*3 10 A*2/A*2 A*2/A*3 A*3/A*3 0 10 A. Calculate the frequency of each allele. B. Determine how many people there would be of each genotype if the population were in Hardy- Weinberg equilibrium and use the Chi-squared test to evaluate how well these expectation fit the observed data
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