2. Show the best method for preparing the following ether via the Williamson ether synthesis. Provide the step by step mechanism for the reactions. -OCH3
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- 1 Provide step by step analysis of each reagent and final product clearly indicatedUsing your reaction roadmap as a guide, show how to convert cyclohexane into hexanedial. Show all reagents and all molecules synthesized along the way.The first widely used herbicide for the control of weeds was 2,4-dichlorophenoxyacetic acid (2,4-D). Show how this compound might be synthesized from phenol and chloro-acetic acid by way of the given chlorinated phenol intermediate.
- H₂C CH3 Show how the compound can be synthesized from benzene and alkyl chlorides.Complete the reaction schemes below providing the reagents required to achieve thetransformation. More than one step may be necessary for each scheme.provide a 5-step synthesis to arrive at the final structure. Provide intermediate steps and show arrow pushing mechanism. Please use the following reagents: 1. Mg, Et2O 2. CO2 3. H3O+ 4. SOCl2 5. 2 eq of HN(Et)2
- 1. Provide stepwise synthesis including reagents and intermediates for the following syntheses. OH COOHThe structure shown below is of Pitolisant (Waxix®), is a drug to treat narcolepsy. CI Pitolisant – Waxix® Below, see the synthesis of the compound. What are the reactions used? OMs OH OH CI CI O Two Williamson ether synthesis reactions. O Aminal formation followed by an ether interchange reaction. O An SN2 reaction followed by a Williamson synthesis.Give the major organic product of the following reactions. 11 12 13 14 15 N₂H4 KOH PH₂PCH₂, THF KMnO4, H₂O NaOH, H₂O¹ CN KMnO4 H₂O* H₂O*
- a) There are two possible pairs of carbonyl compounds and ylides to prepare the following alkene via Wittig reactions. H CH3 i. Propose both pairs of the starting reactants. ii. The above alkene can be converted to an aldehyde and a ketone. Provide a suitable reagent and reaction condition for the conversion.7. Provide the synthesis for the following product starting with the provide starting material. More than one step is required. Show the mechanism for each reaction. CI- Cl- Starting Material ProductH₂Cr2O7 k. OH 4. Propose a reasonable synthesis of the following ether via Williamson etherification reaction