19-year-old with glucocorticoid resistance due to mutations in the glucocorticoid receptor in the ligand binding domain that markedly decreases the affinity of the receptor for cortisol. Which of the following findings is most likely? Decreased serum ACTH concentration Decreased serum sodium concentration Increased sensitivity to dexamethasone Increased serum cortisol concentration Increased serum glucose concentration

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Chapter21: Medications Used For Musculoskeletal System Disorders
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  1. A 19-year-old with glucocorticoid resistance due to mutations in the glucocorticoid receptor in the ligand binding domain that markedly decreases the affinity of the receptor for cortisol. Which of the following findings is most likely?

    1. Decreased serum ACTH concentration

    2. Decreased serum sodium concentration

    3. Increased sensitivity to dexamethasone

    4. Increased serum cortisol concentration

    5. Increased serum glucose concentration

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