13. Compound 1 is an acetyl protected precursor of the phytonutrient pterostilbene (2), a natural antioxidant founsblueberries. Which reagents would you use to synthesize 1 starting with 3 and 4?SalA) PhB(OH)2, KCO₁B) Pd(OAC)2, 2 PPh₁, K₂COC) Cul, H₂O/H₂0D) NaOEt/EtOH14. Which is a D-sugar?OHO-HOHHO-HHO-HACH₂OHAHAHO---HHO-HH-HO-H15. Which of these compounds is the best Michael acceptor?CH₂OHB16. What is the final product of this reaction sequence?B-OHBCISO₂HNaCNDMSO. This compound does not undergo Diels-Alder reactions berA) it lacks electron-withdrawing groupsB) it lacks strong electronC) It cannot alHO-H-OH-HH-OHH-daC2in-OHCH₂OHC70% H₂SO4refluxHO-HHOHH-OH-HCH₂OHDHO-OH3.DOH

The Heck reaction is the chemical reaction of an unsaturated halide with an alkene in the presence…

13. Compound 1 is an acetyl protected precursor of the phytonutrient pterostilbene (2), a natural antioxidant founs blueberries. Which reagents would you use to synthesize 1 starting with 3 and 4? Shal A) PhB(OH)2, K:CO₂ B) Pd(OAC)2, 2 PPh₁, K₂CO C) Cul, H₂O/H₂0 D) NaOEt/EtOH 14. Which is a D-sugar? .O HO- HOH HO-H A HO H H CH₂OH A 15. Which of these compounds is the best Michael acceptor? A HO- --H HO-H H- -OH HO-H CH₂OH B 16. What is the final product of this reaction sequence? B B CI SO₂H NaCN DMSO . This compound does not undergo Diels-Alder reactions ber A) It lacks electron-withdrawing groups B) it lacks strong electron C) It cannot al HO- HOH -H H-OH H- da C 2 in -OH CH₂OH C 70% H₂SO4 reflux HO -H HOH H-OH -H CH₂OH D HO- OH 3. D OH

13. Compound 1 is an acetyl protected precursor of the phytonutrient pterostilbene (2), a natural antioxidant founs blueberries. Which reagents would you use to synthesize 1 starting with 3 and 4? Shal A) PhB(OH)2, K:CO₂ B) Pd(OAC)2, 2 PPh₁, K₂CO C) Cul, H₂O/H₂0 D) NaOEt/EtOH 14. Which is a D-sugar? .O HO- HOH HO-H A HO H H CH₂OH A 15. Which of these compounds is the best Michael acceptor? A HO- --H HO-H H- -OH HO-H CH₂OH B 16. What is the final product of this reaction sequence? B B CI SO₂H NaCN DMSO . This compound does not undergo Diels-Alder reactions ber A) It lacks electron-withdrawing groups B) it lacks strong electron C) It cannot al HO- HOH -H H-OH H- da C 2 in -OH CH₂OH C 70% H₂SO4 reflux HO -H HOH H-OH -H CH₂OH D HO- OH 3. D OH

Introduction to General, Organic and Biochemistry

11th Edition

ISBN:9781285869759

Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres

Chapter19: Carboxylic Anhydrides, Esters, And Amides

Section: Chapter Questions

Problem 19.37P

See similar textbooks

Similar questions

16-17 Propylamine (bp 48°C), ethylmethylamine (bp 37°C), and trimethylamine (bp 3°C) are constitutional isomers with the molecular formula C3HgN. Account for the fact that trimethylamine has the lowest boiling point of the three and propylamine has the highest.
Thioglycolic acid, HSCH2CO2H, a substance used in depilatory agents (hair removers) has pKa = 3.42. What is the percent dissociation of thioglycolic acid in a buffer solution at pH = 3.0?
When a compound like napihthalene C1oHa is dissolved in t-butyl methyl ether, then that solution is extracted with 3 M NaOH, and then the resulting basic aqueous layer is acidified with 6M HCI, what happens to the acidified aqueous layer? a) The naphthalene stays in the the aqueous layer as C10Ha O b) The naphthalene precipitates out as a solid, C10He O C) Nothing happens to the aqueous layer other than a dramatic raising of the pH d) The naphthalene stays in the aqueous layer as C10H>Na O e) Nothing happens to the aqueous layer other than a dramatic lowering of the pH O) The acid precipitates out as a solid, C10H>Na
Explain why phenol (C6H50H) is substantially more acidic than methanol (CH3OH), but benzoic acid (C6H5CO2H) is not much more acidic than acetic acid (CH3CO2H). Нас — ОН ОН H3C- ОН OH pKa = 15.5 pKa = 10.0 pk = 4.75 pk = 4.2
provide appropriate reagents
Which compound would dissolve best in water? A B C H :0: :o: Η Η Η H :s: Н-с — с —о—Н Н-С— с —с —н Н-с- н | H ОА Ов Ос :o:
Give the product of the following reaction: a 'COOH COOH b COOH COOH KMnO4 но C COOH XX. COOH d
Which reaction will give butanoic acid? A) B) C) D) Br 1. CH3MgBr Na₂Cr₂O7 2. H₂O NaCN Br Mg all of the above Et₂0 H3O+ heat 1. CO₂ 2. H₂O
Br NaoH NH2 H>N (B HYO what is compound A and B?
PQ-16. What is the major product of this reaction? OH (A) (B) 2) H3O+ H (C) (D) H
For example: type 1) reagent; 2) reagent; 3) reagent 1) 2) Br 3) 1) HCN/NACN; 2) H3O+;:
Vancomycin is an important antibiotic. It is isolated from the bacterium Streptomyces orientalis and functions by inhibiting bacterial mucopeptide synthesis. It is a last line of defense against the resistant Staph organisms that are now common in hospitals. OH HO, OH H. NHME NH H NH HO,C- “NH2 Vancomycin aglycon ОН НО In 1999, Professor Dale Boger (The Scripps Research Institute) reported a synthesis of vancomycin aglycon (aglycon = lacking a sugar) involving the following steps, among others. Compound (I) was prepared from simple starting materials by a series of steps involving forming amide bonds.