107. An investigator is conducting a study of the effects of alcohol consumption in young adults. A total of 250 participants between the ages of 21 and 25 years are recruited for the study. Blood alcohol concentrations are measured using a Breathalyzer after repeated oral doses of pure (95%) ethanol. Results show that female participants become more intoxicated and have higher blood alcohol concentrations compared with male participants receiving an equivalent dose of ethanol. Which of the following characteristics of the female participants best explains these findings? 4 A) Decreased alcohol dehydrogenase activity B) Induction of enzymes in the microsomal ethanol-oxidizing system C) Presence of genetic polymorphisms of alcohol dehydrogenase D) Presence of genetic polymorphisms of aldehyde dehydrogenase E) Relatively higher proportion of total body water

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107. An investigator is conducting a study of the effects of alcohol consumption in young adults. A total of 250 participants between the ages of 21 and 25 years are recruited for the
study. Blood alcohol concentrations are measured using a Breathalyzer after repeated oral doses of pure (95%) ethanol. Results show that female participants become more
intoxicated and have higher blood alcohol concentrations compared with male participants receiving an equivalent dose of ethanol. Which of the following characteristics of the
female participants best explains these findings?
4
A) Decreased alcohol dehydrogenase activity
B) Induction of enzymes in the microsomal ethanol-oxidizing system
C) Presence of genetic polymorphisms of alcohol dehydrogenase
D) Presence of genetic polymorphisms of aldehyde dehydrogenase
E) Relatively higher proportion of total body water
Transcribed Image Text:107. An investigator is conducting a study of the effects of alcohol consumption in young adults. A total of 250 participants between the ages of 21 and 25 years are recruited for the study. Blood alcohol concentrations are measured using a Breathalyzer after repeated oral doses of pure (95%) ethanol. Results show that female participants become more intoxicated and have higher blood alcohol concentrations compared with male participants receiving an equivalent dose of ethanol. Which of the following characteristics of the female participants best explains these findings? 4 A) Decreased alcohol dehydrogenase activity B) Induction of enzymes in the microsomal ethanol-oxidizing system C) Presence of genetic polymorphisms of alcohol dehydrogenase D) Presence of genetic polymorphisms of aldehyde dehydrogenase E) Relatively higher proportion of total body water
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