10-year-old female was admitted due to episodes of generalized seizure-like activity that started a day prior to admission. 14 days prior to admission(PTA), she was playing with friends in their backyard when an object cut her leg. Despite having a deep cut, she continued on her game. 10 days PTA, she experienced stiffness of the neck, difficulty of  swallowing and chewing. the signa and symptoms persisted until 7 days PTA, when she experienced abdominal rigidity, sweating, fever and tachycardia. the patient condition worsened until admission. Questions: discuss the significance of soluble NSF (Nephrogenic Systemic Fibrosis) attachment receptor protein (SNARES) in the release of neurotransmitters Discuss the different of EPSP and IPSP, and its ionic basis explain the manifestation cited in the case to tetanus and its pathophysiology    Differentiate the type of paralysis that occur in tetanus and botulism

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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10-year-old female was admitted due to episodes of generalized seizure-like activity that started a day prior to admission. 14 days prior to admission(PTA), she was playing with friends in their backyard when an object cut her leg. Despite having a deep cut, she continued on her game. 10 days PTA, she experienced stiffness of the neck, difficulty of  swallowing and chewing. the signa and symptoms persisted until 7 days PTA, when she experienced abdominal rigidity, sweating, fever and tachycardia. the patient condition worsened until admission.

Questions:

  1. discuss the significance of soluble NSF (Nephrogenic Systemic Fibrosis) attachment receptor protein (SNARES) in the release of neurotransmitters
  2. Discuss the different of EPSP and IPSP, and its ionic basis
  3. explain the manifestation cited in the case to tetanus and its pathophysiology   
  4. Differentiate the type of paralysis that occur in tetanus and botulism
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