1.2 The following is a drug used to treat multi-drug resistant strains of Falciparum malaria CH3 H3C a) b) b) c) O- -O O H O H "H CH3 What is the name of the drug and what group of compounds does it belong to? What is it often used for? Which South African plant is the drug isolated from? Indicate whether this compound is a primary or secondary metabolite and explain your answer?

1.2 The following is a drug used to treat multi-drug resistant strains of Falciparum malaria CH3 H3C a) b) b) c) O- -O O H O H "H CH3 What is the name of the drug and what group of compounds does it belong to? What is it often used for? Which South African plant is the drug isolated from? Indicate whether this compound is a primary or secondary metabolite and explain your answer?

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter25: Carbohydrates

Section: Chapter Questions

Problem 25.44P: Digitalis is a preparation made from the dried seeds and leaves of the purple foxglove, Digitalis...

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Digitalis is a preparation made from the dried seeds and leaves of the purple foxglove, Digitalis purpurea, a plant native to southern and central Europe and cultivated in the United States. The preparation is a mixture of several active components, including digitalin. Digitalis is used in medicine to increase the force of myocardial contraction and as a conduction depressant to decrease heart rate (the heart pumps more forcefully but less often).
4) Multistriatin, one of the pheremones of the elm bark beetle, is a volatile compound released by a virgin female beetle when she has found a good food source - an elm tree. Male beetles, which carry the Dutch elm disease fungus, are attracted by the pheromone; the tree becomes infected with the fungus and soon dies. Multistriatin is used to trap the beetles, but the amount in beetles is so miniscule that the compound must be synthesized. The following synthesis of multistriatin uses only chemistry that we have seen in Chem 348. HO. НО Br type O type. H type H H CH3 H HO HO type O H CH3 "Η OH type H hint: anhydrous cond CH3 H = H type type HO CH3 H H type CH 3 H Multistriatin Multistriatin
What is the product of the following reaction? 1) NaOCH2CH3 2) H30® ? 1) 2) 3) 4) Select an answer and submit. For keyboard navigation, use the up/down arrow keys to select an answer. a Compound 1) b Compound 2) Compound 3) d Compound 4)
Enanthotoxin is an extremely poisonous organic compound found in hemlock water drop- wart, which is reputed to be the most poisonous plant in England. It is believed that no British plant has been responsible for more fatal accidents. The most poisonous part of the plant is the roots, which resemble small white carrots, giving the plant the name"five finger death."Also poisonous are its leaves, which look like parsley. Enanthotoxin is thought to interfere with the Nat current in nerve cells, which leads to convulsions and death. он How many stereoisomers are possible for enanthotoxin?
2) Use compound C (shown below) to answer the following questions. H2N H CH3 compound C H" H3C Br a) Classify compound C as a primary, secondary or tertiary amine. b) Give the IUPAC name for compound C, omitting absolute configuration (R or S) designations. c) In the indicated spaces below, draw the enantiomer, a diastereomer and a Fischer projection of compound C. enantiomer of compound C diastereomer of compound C Fischer projection of compound C
Answer the following :(i) Why is the use of aspartame limited to cold foods and drinks?(ii) How do antiseptics differ from disinfectants?(iii) Why do soaps not work in hard water?
What is the relationship between Compound 1 and Compound 2?
Given that C6H11COOH has a pKa = 4.8 and C6H11N+H3 has a pKa = 10.7, (a) What pH would you make the water layer to cause the carboxylic acid to dissolve in the water layer and the amine to dissolve in the ether layer? (b) What pH would you make the water layer to cause the carboxylic acid to dissolve in the ether layer and the amine to dissolve in the water layer?
7. (a) for which of the following compounds is it hazardous to breathe dust/ vapor/ fumes: acetylsalicylic acid, salicylic acid, acetic anhydride, acetic acid, phosphoric acid? (b) based on the boiling point or melting point of the compounds, which are you most likely to inhale accidentally? (c) based on GHS hazard information, which would be most dangerous to inhale? (d) of all these chemicals, which is most important to handle in a fume hood?
Refer to the following information to answer questions 1 to 9: As a biotechnologist working for a pharmaceutical company, you as tasked with preparing the cardiac antiarrhythmic agent Amelfolide from p-nitrobenzyl chloride and 2,6-dimethyl aniline (Figure 2.1). You are provided the starting materials and asked to prepare 7.50g of pure material. No other instructions are given to you. MW 2,6-dimethylaniline = 121.18 g/mol MW p-nitrobenzyl chloride = 185.56 g/mol MW Amelfoliode = 270.29 g/mol %3D NH2 CI O2N O2N When developing a synthetic scheme, the first thing to do is check the scientific literature to see if someone has done this reaction before you. Upon performing a literature search, you identify a publication where a group from Japan has performed the same reaction you are tasked with completing. The paper is in Japanese and you cannot read the details of the procedure, however, you can make out that the reaction is performed using DCM as the solvent and proceeds with a yield of…
22:22 Tue 11 Jan * 84% Done Assignment 3 (3 of 9) 1. Identify the functional groups in the following molecules: (a) (b) (c) H. H С—ОН С-ОН Н-С—ОН C=C H H HO-C-H C-CH3 Н-С—ОН Acrylic acid (2 functional groups) H-C-OH Aspirin (3 functional groups) CH2OH Glucose (6 functional groups) 2. Identify the carbon atoms in the following molecules as primary, secondary tertiary, or quaternary: (a) CH3 (b) CH3CHCH3 (c) CH3 CH3 CH3CHCH2CH2CH3 CH3CH2CHCH2CH3 CH3CHCH,CCH3 ČH3 3. Give IUPAC names for the following alkanes: (a) CH3 (b) CH3 CH3CHCH2CH2CH3 CH3CH2ĊCH3 ČH3 (c) H3C CH3 (d) CH2CH3 CH3 CH3CHCCH2CH2CH3 CH3CH2CHCH2CH2CHCH3 CH3 (e) CH3 CH2CH3 (f) H3C CH3 CH3CH2CH2CHCH2CCH3 CH3C-CCH2CH2CH3 CH3 H3C CH3 4. Draw structures for the following substances: (a) 2-Methylheptane (c) 4-Ethyl-3,4-dimethyloctane (e) 1,1-Dimethylcyclopentane (b) 4-Ethyl-2-methylhexane (d) 2,4,4-Trimethylheptane (f) 4-Isopropyl-3-methylheptane