1. There are two different variations at STR locus THO1. Where did these variations come from?b) The STR locus D21S11 only has one variation. Why? Allelic ladder All possible results for each of the 16 DNA loci100120 140 160 180 200D3S1358THO112 15 18 468 1113 16 1914 17 20AD5S818791148 10 13 1612 15VWAX 10 13 16 19 22Y11 14 17 2012 15 18 21220 240 260 280D21S1124 27 30D13S317www.25.2 29.12 1530.2 34.231.2 35.2791 14 6 8 10 138 10 137 9 11 1412D7S820D8S11797911 14 178 10 13 1612 15 18300D16S5398 11 14 17 20 23 2610 13 16 19 22 2510.2TPOX5 8 10 13911 1468 1179 1210320 340D18S5113.212 15CSF1P036016380 400 420Penta E21.225.26 8 10 13 22 5 7 9 11 13 15 173.28 10 12 14 1612 155 7 9 11 13 15 17 19 21 246 8 10 12 14 16 18 20 22FGA25 28 31.2440Penta D460 480A900E-600-300B-900E-600300сE-900-600-30060004000-200060004000+2000-1.54000+2000D351358100100100X141723118.30151409122.48Power Plex_16_ID3.2.0D55818112042128 49THOIPower Plex 16 ID3.2.0VWA172463168 401095175.26D135317112317186.82D21511200200302543222.87200D75820D$$1179101541227.32111184231.4513D165539ΤΡΟΧAD18551112233285.13121625209.1330030030015191445 1348311.27 326.82CSFIPOFCA101517333.0912834341.2123Penta BPenta D400400400121550411.16131420416.0911104409.21125177414.04ABC To match DNA samples from a crime scene, forensic scientists analyze the number of repeats at 16 ormore STR loci. Today's technology can measure up to six loci at once. Row A from Handout 2-2 (below)shows the variations at five STR loci for one person. The name of each STR locus is in the gray box.D351358100141723118.30151409122.48100120 140D3S1358THOI12 13 1913 16 1914 17 202463168.409.31095175 26160D21511200THO1302543222.87The first STR locus (D3S1358) is on chromosome 3 where the sequences TCTG and TCTA are repeated2 to 15 times. Scientists use polymerase chain reaction (PCR) to amplify the DNA that includes thisregion. The PCR products are separated by size and charted on an electropherogram (or e-gram). Thepeaks on the left are the smallest DNA fragments (those with fewer repeats). The peaks on the rightare the largest (with more repeats).D21S11Ludmila0001 24 27 30 35 36372 133 2624.2Nine common variations are found at D3S1358. The allelic ladder e-gram below is not from oneperson, but shows all the possible variations at each of the five STR loci. Each variation is identifiedwith a number. The person above has variation 14 (shown as the first number in the box below thegraph) at the D3S1358 locus on one copy of chromosome 3 and variation 15 on the other.25.231.2 35.2D1855139300280151445191348311 27 326 82300 320 340D18S51360литатлииииииPenta E011 14 17 20 23 269 12 15 18 21 24 2710 13 16 19 22 2510.24001550411 16131420380416.09400 420 440 460 480Penta EEllii3 15 17 19 21 26 8 10 12 14 16 18 20 2223

Name: 1. There are two different variations at STR locus THO1. Where did the
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Description: 1. There are two different variations at STR locus THO1. Where did these variations come from?b) The STR locus D21S11 only has one variation. Why? Allelic ladder All possible results for each of the 16 DNA loci100120 140 160 180 200D3S1358THO112 15 1

The variations at STR locus THO1 come from the inheritance of alleles from the individual's parents.…

Answered: 1. There are two different variations…

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1. There are two different variations at STR locus THO1. Where did these variations come from? b) The STR locus D21S11 only has one variation. Why?

Anatomy & Physiology

1st Edition

ISBN:9781938168130

Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Chapter21: The Lymphatic And Immune System

Section: Chapter Questions

Problem 34RQ: Which of the following terms means many genes? polymorphism polygeny polypeptide multiple alleles

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Which of the following terms means many genes? polymorphism polygeny polypeptide multiple alleles
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