1. The acid catalyzed synthesis of diethyl ether occurs via and Sn2 reaction although a protic solvent is used. Discuss in your group why this substitution cannot occur via an SN1 reaction, and why E1 and E2 reactions do not occur. Your answer should be in complete sentences and use appropriate vocabulary to describe the molecules involved. 2 H,SO4(aq) + H2O

1. The acid catalyzed synthesis of diethyl ether occurs via and Sn2 reaction although a protic solvent is used. Discuss in your group why this substitution cannot occur via an SN1 reaction, and why E1 and E2 reactions do not occur. Your answer should be in complete sentences and use appropriate vocabulary to describe the molecules involved. 2 H,SO4(aq) + H2O

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter17: Carboxylic Acids

Section: Chapter Questions

Problem 17.23P

See similar textbooks

Similar questions

Substitutions on aromatic rings are generally carried out by electrophilic substitution, but for the synthesis of phenolic compounds and alkoxy benzene it is carried out by nucleophilic substitution, explain why this is so .
(b) Answer the following questions based on the compounds below. Jawab soalan berikut berdasarkan kepada sebatian di bawah. CI CI A в (i) Which compound has the higher boiling point? Explain. Sebatian manakah mempunyai takat didih yang lebih tinggi? Terangkan. (ii) Draw the SN2 mechanism for the reaction of compound A with sodium hydroxide, NaOH. Lukis mekanisma Sn2 bagi tindak balas antara sebatian A dengan natrium hidroksida, NaOH.
Q4. Nucleophilic attack at carbonyl with loss of carbonyl oxygen. For this question, answer AT LEAST FIVE of the SIX parts. (a) For the FOUR reactions listed below, draw structures of the major organic products. (i) (ii) (iii) HO OH ●... NMe₂NH₂ cat. dry HCI H Ph₂pⓇ THF
Organoboranes, such as 1 or 2, are Lewis acids and are observed to be electrophilic in their reactions with other compounds, esp. alkenes. Using your knowledge of molecular structure, explain this observation. That is, what makes organoboranes such good Lewis acids?
Draw the organic product expected from the reaction. Include all hydrogen atoms. Note that K2Cr2O7K2Cr2O7 is present in excess. CH3CH2CH2OH+K2Cr2O7(aq) −→−−−H2SO4
3. It is required to introduce a halogen group to a five membered ring, thiophene. Discuss the reaction mechanism involved in the reaction by selecting a suitable halogen group and analyze why a particular substituted product obtained after the reaction is predominant over the other possible product(s) with the help of reactions. To meet the ever increasing demand of global population, the demand for textile products and consumption of dyes by these industries is increasing.
The nitro groups on the benzene ring in the reactant serve two purposes.One is to let you know what atoms in the reactant correspond to what atomsin the product. But what role do the nitro groups play electronically – whywould the reaction be much slower if these nitro groups weren’t attached tothose benzene carbons? Draw any relevant structures to support youranswer.
2. a) Illustrate a synthesis of each of the following molecules which utilizes phenylmagnesium bromide as the source of the benzene rings. Ph,COH Ph₂C=CH₂ PhCH₂CH₂OH Ph(CH,)C=CH,
b) Esters can undergo hydrolysis to give an alcohol and a carboxylic acid. Lactone P which is a cyclic ester, can undergo base-catalyzed hydrolysis to give a hydroxy carboxylic acid. Write the plausible mechanism for the transformation.
Each of the following reactions has been described in the chemical literature and involves an organic reactant somewhat more complex than those we have encountered so far. Nevertheless, on the basis of the topics covered in this chapter, you should be able to write the structure of the principal organic product of each reaction.
(a) What reagents would be used for the conversion of alkene A into the target? (b) What reaction is involved in the conversion of alcohol B into alkene A? Suggest a reagent that might affect this transformation. (c) Give a retrosynthetic analysis showing the disconnection of B, the synthons produced that lead to the synthetic equivalents given (draw their structures).
Q2) Write a reaction for the following, with explanation. part 1) Dimethyl ketone with Hydrogen cyanide (HCN) part2) Preparation of M. nitro chlorobenzene from benzene, using nitric acid Sulfuric acid, Chlorine, AICI, and any reagent you need. part3) Solvation of ethylene epoxide in acidic medium