1. For the following reaction step, indicate which pattern of arrow pushing it represents. a. proton transfer b. rearrangement c. loss of a leaving group 2. Melphalan, a drug used in chemotherapy, reacts with itself in the body before binding with its target, as illustrated in the mechanism below. What is the first pattern of arrow pushing seen in this reaction? a. rearrangement b. loss of a leaving group c. nucleophilic attack

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