1 Drag items from the column on the right to the left to match the pairs Tetrodotoxin Cholera Toxin Pertussis Toxin Beta-blockers BOTOX Blocks aceylcholine release Prevents G-alpha-i from binding GTP. G-alpha-i is unable to inhibit adenylyl cyclase. Results in increased cAMP (mostly in lung cells) Blocks a receptor that activated G-alpha-s, thus, prevents the activation of G-alpha-s. Results in decreased cAMP (mostly in heart cells) Blocks voltage gated sodium channels Prevents G-alpha-s from hydrolyzing GTP. G-alpha- s can't turn off. Results in massive increase of CAMP (mostly in intestinal cells)

Organic And Biological Chemistry
7th Edition
ISBN:9781305081079
Author:STOKER, H. Stephen (howard Stephen)
Publisher:STOKER, H. Stephen (howard Stephen)
Chapter10: Enzymes And Vitamins
Section: Chapter Questions
Problem 10.43EP
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1
Drag items from the column on the right to the left to match the pairs
Tetrodotoxin
Cholera Toxin
Pertussis Toxin
Beta-blockers
BOTOX
Blocks aceylcholine
release
Prevents G-alpha-i from
binding GTP. G-alpha-i is
unable to inhibit adenylyl
cyclase. Results in
increased cAMP (mostly
in lung cells)
Blocks a receptor that
activated G-alpha-s, thus,
prevents the activation of
G-alpha-s. Results in
decreased cAMP (mostly
in heart cells)
Blocks voltage gated
sodium channels
Prevents G-alpha-s from
hydrolyzing GTP. G-alpha-
s can't turn off. Results in
massive increase of
CAMP (mostly in intestinal
cells)
Transcribed Image Text:1 Drag items from the column on the right to the left to match the pairs Tetrodotoxin Cholera Toxin Pertussis Toxin Beta-blockers BOTOX Blocks aceylcholine release Prevents G-alpha-i from binding GTP. G-alpha-i is unable to inhibit adenylyl cyclase. Results in increased cAMP (mostly in lung cells) Blocks a receptor that activated G-alpha-s, thus, prevents the activation of G-alpha-s. Results in decreased cAMP (mostly in heart cells) Blocks voltage gated sodium channels Prevents G-alpha-s from hydrolyzing GTP. G-alpha- s can't turn off. Results in massive increase of CAMP (mostly in intestinal cells)
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