A) Meiosis consists of two cell divisions and is broken up into Meiosis I and Meiosis II. At the beginning of the Cell Cycle, in this case there are four chromatids each from the homologous pairs being A, a, B, b. This is the Diploid number (4) meaning it is 2 times the haploid number that will be seen at the end of meiosis II. During the S phase of interphase, the chromatids replicate and reach the end of G2 phase. Now starting meiosis, during the first stage of prophase I the chromosomes condense and pair up through synapsis with their sister chromatids creating AA, aa, BB, bb. After they pair up they go through a process called crossing over, where the homologous chromosomes share a piece of their genetic material with each other. Crossing over allows for the genetic diversity of chromosomes. Now there are four homologous chromosomes Aa, Aa, Bb, Bb, each containing heterozygous alleles because the sister chromatids exchanged genetic information with their homologous pair. During late prophase I, spindle fibers being to form where they will later attach to a homologous chromosomes centromere. The next stage is Metaphase I. During metaphase I, the homologous pairs line up at the metaphase plate, also known to be the center of the cell. The homologous pairs form a tetrad which is considered a group of four homologous chromosomes. These homologous chromosomes orient themselves randomly, which is know as the process of independent …show more content…
The genetic disorder is caused by a mutation in the DNA segment CAG found in chromosome 4 which results nerve cell death. Phenotypic characteristics include gradual motor dysfunction, psychological issues that correlate to degeneration of metal health, and cognitive degeneration. Studies on transgenic mice have allowed a better understanding of the proteins that relate to Huntington’s
Chromosome pairs line up across the equator of the spindle at metaphase I (5). In anaphase I the chromosomes separate and travel to opposite ends of the spindle. The chromosomes migrate to the equators of two new spindles for metaphase 2 (7). Next the chromatids are pulled apart in anaphase 2 to form four clusters of chromosomes in telophase 2. The nuclear envelopes reform around four haploid nuclei that will give rise gamete
Exercise 3B is a study of meiosis. You will simulate the stages of meiosis by using chromosome models. You will study the crossing over and
Meiosis consists of one DNA replication and two nuclear divisions resulting in 4 daughter cells. The process which provides for genetic variation is crossing over. Crossing over occurs in the early stages when homologous chromosomes move together so that their chromatids form a tetrad. This is called synapsis and allows for the exchange of chromosome sections.
Huntington’s Disease is a brain disorder affecting movement, cognition, and emotions (Schoenstadt). It is a genetic disorder generally affecting people in their middle 30s and 40s (Sheth). Worldwide, Huntington’s disease (affects between 3-7 per 100,000 people of European ancestry (Schoenstadt). In the United States alone, 1 in every 30,000 people has Huntington’s disease (Genetic Learning Center). Huntington’s Disease is a multi-faceted disease, with a complex inheritance pattern and a wide range of symptoms. There is also much research being done in the field of Huntington’s disease, because as of 2012, this disease is untreatable. THESIS.
These bivalents line up along the equator during metaphase I, the arrangement of the bivalent is completely random and relative to the orientation of the other bivalents, this is known as the independent assortment of chromosomes. This is followed by anaphase I where the homologous chromosomes separate and move to the opposite poles of the cell. At telophase I the cell divides into two, each cell contains one chromosome from each homologous pair. The second stage of meiosis is similar to mitosis.
Translation is a task that makes ribosomes synthesize proteins utilizing mRNA transcript made during transcription. In the begining of this task mRNA attaches it self to a ribosome so that it can be reveal a codon (three nucleotides).
D) Sexual reproduction is more likely to increase genetic variation than is asexual reproduction. E) Only asexual
Huntington's Disease (HD) is an autosomal dominant, progressive, neurodegenerative disorder (Walker, 2007 and Harmon, 2007). The gene that causes the disease is located on the fourth chromosome and causes an abnormal number of repeats in the patient's genetic code (Harmon, 2007). Huntington's Disease can have devastating effects on patients' quality of life. The first symptoms of HD generally start between the ages of 30 and 45 and patients are typically asymptomatic prior to this time (Terrenoire, 1992 and Walker, 2007). However, the disease progresses with subtle changes in motor control, personality, and cognition. Patients eventually develop distinct
[A labelled diagram of the end of the Prophase stage of a cell here would be
Mitosis is one of two main methods of cell replication, the other being meiosis. It is “the simple duplication of a cell and all of its parts” resulting from the splitting of a cell. The ‘parent’ or original cell splits, duplicating its DNA (packaged in chromosomes) producing two ‘daughter’ or new cells with the same genetic code. There are four stages of mitosis; Prophase, Metaphase, Anaphase and Telophase. Interphase is not an official phase of mitosis as the cell is at ‘rest’ and not being divided during this phase. It is often called one of the phases of mitosis as it is one of the stages in the life cycle of a cell; however it is not a phase of mitosis due to the fact that no division takes place.
Huntington's disease is an autosomal dominant disorder, which is found on the # 4 chromosome. George Huntington discovered it in 1872. It mainly has an effect on the nervous system. There are around 210,000 bases between D4S180 and D4S127. The disease itself is found in 2% of people in their childhood, and in 5% of the people they were older then 60. (Miller p 16) In the majority of the affected people the disease is detected between the ages of 35-45. In males the disease begins around the time of their childhood. However, in females it begins later in life. This severe symptom has a tendency for the condition to worsen as it is passed on from generation to generation. Huntington’s disease is paternally
This happens in meiosis 2 which happens after meiosis 1. Metaphase 2 happens after prophase 2. In metaphase 2 spindle fibers form from the centrioles which are found on the opposite ends of the cell and grab the chromosome at the kinetochore region on the centromere. Once the cell grabs the chromosomes they align them at the center of the cell at the equator. Spindle fibers attach to the kinetochore of each of the chromosome and align it in the center. Anaphase 2 happens after metaphase 2. In anaphase 2 the spindle fibers begin to contract in which they move and separate the 2 chromatids within the chromosome. The spindle fibers then pull on the chromosome on both ends and separate the chromatids. In anaphase 2 the chromatids are genetically
When I read “The Egg and the Sperm: How Science has Constructed a Romance Based on Stereotypical Male-Female Roles” by Emily Martin, I initially thought of the many instances in science fiction where males have a dominant role and females have a less successful role. For example, this is wonderfully shown in the Matrix where Neo has a prophecy of being the one and Trinity having a prophecy of falling in love with the one. Neo has a fate that is all about him while Trinity has a fate that revolves around Neo rather than herself. However, after getting past the typical role of gender, the role of sexuality and reproduction came to my mind and I thought of the Futurama episode called “Amazon Women in the Mood,” which flips the stereotypical gender
biased between the male and the female reproductive biology. The article focuses on the role of
The job in meiosis in regards to the homologous and sister chromatids is done by a two-step division process. During the first step the homologous pairs de-attach and this is called meiosis