Abstract Osteomyelitis is a broad and debilitating disease typically triggered by a variety of conditions. Osteomyelitis starts off as inflammation seen within bone and bone marrow that can quickly progress into a large, subclassified infection. The length of time the infection has been present in the body and whether or not there is a pus formation or increased density among the infected bone is commonly used to classify severity. Pyrogenic bacteria or mycobacteria systematically attack the route and anatomic location of the infection evolving acute conditions into chronic ones. “Staphylococcus Aureus is a gram-positive, round shaped, non-mobile cocci typically found in clusters inside these wounds. Staphylococcus Aureus is one of the most common causes of infections after injury or surgery and affects nearly 500,000 patients in hospitals each year. Staphylococcus Aureus belongs to the family Staphylcoccaceae and survives by affecting all known mammalian species including humans” (www.news-medical.net). Osteomyelitis can start in one area of the body while spreading through the blood stream into other bone regions. Typical treatment options for Osteomyelitis includes antibiotics, removal of …show more content…
Bones can become infected with Osteomyelitis through the blood stream by an open fracture or surgical wound. “Only two out of every 10,000 people acquire Osteomyelitis in a lifetime. The condition affects children and adults but in different ways. Certain conditions and behaviors can weaken the immune system increasing an individual’s risk of obtaining Osteomyelitis such a diabetes mellitus, alcoholism, hemodialysis, rheumatoid arthritis, HIV/AIDS, sickle cell anemia, or a lack of blood supply (www.wedmd.com). In children, Osteomyelitis is usually acute and very easy to treat showing signs in the bones of the arms and legs. In adults, Osteomyelitis can also be acute or chronic and can persist due to a reoccurring medical
There are numerous causes of osteopenia. Usually as people age, naturally their bones become weaker and thinner, more susceptible to breaking. Around the age of 30, all people begin to reach their peak bone density. The thicker and stronger your bones are, the less likely you are able to develop the disease. Women are more than twice as likely to be diagnosed with the disease because Women have a significantly lower peak bone density and the deterioration of bone mass speeds up as hormonal changes that occur during the time of menopause. It is also becoming more common in young female athletes. Young female athletes that
Methicillin-resistant Staphylococcus aureus, or more commonly, MRSA, is an emerging infectious disease affecting many people worldwide. MRSA, in particular, is a very interesting disease because although many people can be carriers of it, it generally only affects those with a depressed immune system; this is why it is so prevalent in places like nursing homes and hospitals. It can be spread though surgeries, artificial joints, tubing, and skin-to-skin contact. Although there is not one specific treatment of this disease, there are ways to test what antibiotics work best and sometimes antibiotics aren’t even necessary.
skin condition that staph is able to cause is cellulitis. It is more common in people who have a weakened immune system such as people who are immunocompromised, infants, and the elderly. Cellulitis is characterized by a red, warm patch on the skin paired with a fever. “The bacteria that cause cellulitis can spread rapidly, entering lymph nodes and your bloodstream. Recurrent episodes of cellulitis may cause chronic swelling of the affected limb” (Mayo, 2015). Cellulitis is spread extremely easily, and is a big issue within long term care facilities. The infection can be cured by antibiotics. However, there are cases reported stating that cellulitis is becoming resistant to some antibiotics. The doctor can order a culture to send to pathology.
1. A healthy high school athlete is diagnosed with fever and cellulitis of the right knee. The infection is resistant to oral antibiotics. He then develops osteomyelitis of the right knee. If untreated, the infection could result in
Skin and or soft tissue infections often occur following a break in normal skin integrity from either trauma or skin disease (Brown & Ebright, 2002). The vast majority of these infections are caused by the gram-positive bacteria Staphylococcus aureus, part of the normal flora existing on the skins surface. Abscess has been found to be the most commonly found SSTI in PWID (Brown & Ebright, 2002). Symptoms of abscess include pain and or tenderness at and around the site of infection, swelling, and redness topped with a pustule. If left untreated, spread and progression of the SSTI leading to tissue ischemia and death, gangrene, sepsis and death can occur (Brown & Pieper, 2002). Hospital treatment of a SSTI is costly. Analysis of the Nationwide Inpatient Sample by the Agency for Healthcare research estimated that in 2009, costs associated with hospital treatment of SSTI reached an estimated $4.8 billion, which is approximately $11,000 per patient (Suya et al., 2009).
Osteopenia is a disease in which the bone density in a person is lower than normal but not so low to where they would be considered to have osteoporosis. To tell the difference between these similar disease you would have to speak with your doctor and schedule a bone density test. By measuring your bone density you will see how dense and how strong your bones are with having osteopenia over time the bones in the body will grow weak and be more prone to breaking as well with the lowering of bone density with having osteopenia it will develop into osteoporosis over time due to the low bone density. The causes of osteopenia are natural in everyone. As we get older are bones start to lose density around are middle aged years they start to become
The first known case of osteopetrosis was reported by the German radiologist Albers-Schönberg. Osteopetrosis, by definition, is, "a disorder in which an imbalance in the formation and breakdown of bone causes bones to be overly dense, yet weak and prone to break easily". There are two main forms that osteopetrosis comes in: malignant infantile and adult. The malignant infantile form can diagnosed during or shortly after birth and can immensely shorten the infant's life expectancy. The more formal name for the malignant infantile form is, autosomal recessive osteopetrosis. The other major form, the adult form, seems to be more milder and may not be diagnosed until adolescence or adulthood. The formal name for the adult form is, autosomal dominant osteopetrosis. There are a variety of different symptoms that can become apparent but the most common symptoms seem to be: bone fractures, low blood cell levels, impaired vision and hearing, and dental problems related to infection. I have already stated how the malignant infantile form is diagnosed, but how is the adult form diagnosed? It seems that, bones in patients with osteopetrosis appear abnormally dense and chalky whitish on x-rays. Bone biopsies are generally not recommended. Doctors may also use other tests to diagnose and gain additional information about specific problems that are related to osteopetrosis.
The span of this narrative takes place Thirty years prior to current time, in Two Thousand and Seventeen. At the time I was a young and well educated Osteopathic surgeon, however I had quite little experience with the field as the majority of patients came for infections in the foot rather than bone and muscle pain. I remember I had a child patient on the first week of 2017, a young man no older than 5 with a horrid infection within his big toe due to the digging of the nail. But nitrogen wasn’t able to fix it, so he had to have a quarter of his foot removed in an unnecessarily long procedure. This wasn't the first time this had happened, however I had grown tired of infection. Only people who deserved a bad condition should have it.
My right foot was put in a cast in order to help my 5th metatarsal heal. As a result I developed an ulcer and Osteomyelitis in the bone of my 3rd metatarsal and
Osteogenesis imperfecta (OI) is a disease that causes your bones to break easily, it is also known as brittle bone disease, fragilitas ossium and vrolik disease. OI typically is considered to be a dominantly inherited disorder. Most cases of OI that have been reported have an autosomal dominant pattern. Many people who have this disease have it because they have inherited a mutation from their parent. In some cases, it may have an autosomal recessive pattern. This would be cased due to both parents carrying one copy of the gene. The genes affected are COL1A1, COL1A2, CRTAP, and P3H1.
I have enjoyed reading your post, Kerry. I found your comment on Osteomyelitis informative and thought provoking. As you have stated, Osteomyelitis is an infection of the bone that may start in the bone or may be a result of an infection that has started elsewhere in the body and traveled through the blood stream to the bone. Osteomyelitis may be difficult to treat as it is sometimes located deep in the bone. Osteomyelitis most likely affects long bones in children while affect the vertebrae in adults. Diabetics may develop osteomyelitis in their feet. Osteomyelitis may be difficult to treat; however, it may be treated successfully with strong intravenous antibiotics combined with surgery (Arias, Betancur, Pinzón, Arango, & Prada, 2015). Risk
S. aureus responsible for 70% skin infection in children, moreover, the incidence of skin infection caused by MRSA is in a continuous increasing (Nataraj et al., 2014). Pseudomonas aeruginosa is gram-negative bacteria, it is classic opportunistic bacteria and are often severe, life-threatening and difficult to treat due to it has an innate resistance to many of antibiotic and disinfection (Bangera D et al., 2015; Wendell Lou B. Ladion et al., 2015). P. aeruginosa recently acquired significant as one of the most important organisms that cause nosocomial infection due to having an ability to survive in hospital environments, in addition, it has the ability to develop resistance against many antimicrobial agents (Nagoba et al., 2013). Wound infection caused by P. aeruginosa rapidly deteriorating and lead to systemic spread and therefore death within days or weeks (Turner et al., 2014). Escherichia coli is gram negative bacteria and considered as a member of the Enterobacteriaceae, it is innocuous resident in a gastrointestinal tract, but at the same time has the ability to cause
Osteitis fibrosa cystica is a skeletal manifestation of advanced hyperparathyroidism. OFC was first described in the 19th century. It can be detected through a combination of blood testing, x-rays, and also tissue sampling. Did you know before 1950, around half of the people diagnosed with a disease called hyperparathyroidism in the United States saw it progress to OFC, but with early identification techniques and improved treatment methods, instances of OFC in developed countries are increasingly rare. OFC was discovered by Friedrich Daniel von Recklinghausen in 1890. Although a man name William Hunter who did in 1783 was first given credit for finding the first example of the disease.
Hospitalizations: The patient was hospitalized in 1984 for two weeks for Osteomyelitis. He had to undergo surgery to remove the infection in the proximal portion of his left tibia..
They have diminished inflammatory response even when extreme soft tissue and bone infection are present. Identification of foot infections in the patient with diabetes mellitus requires vigilance because the signs of infection may not be present ( Baranoski and Ayello, 2003,p.327). The most common bacteria found in non-limb threatening infection are Staphylococcus and Streptococcus. These infections should be treated with oral antibiotics. If the limb is threatened with the infection, parenteral antibiotics and surgical debridement of necrotic tissue needs to be executed. Most limb threatening infections are polymicrobial. Staphylococcus aureus, group B atreptococci, Enterococcus, and facultative Gram-negative bacilli are the major pathogens involved in these types of