1. The act or process of administering, especially the management of a government or large institution. 2. The activity of a government or state in the exercise of its powers and duties. 3. often Administrationa. The executive branch of a government. b. The group of people who manage or direct an institution, especially a school or college. 4. The term of office of an executive officer or body. 5.Law Management and disposal of a trust or estate. 6. The dispensing, applying, or tendering of something, such as an oath, a sacrament, or medicine.